Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells
Dual targeting of p53 and c-Myc selectively can eliminate leukaemic stem cells
ARTICLES
Induction of p53 suppresses chronic myeloid leukemia
January 13, 2017, PublMed
Glasgow University researchers make significant breakthrough in cure for leukaemia
June 9, 2016, DailyRecord
Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
June 8, 2016, Nature
Scientists identify drugs to target ‘Achilles heel’ of Chronic Myeloid Leukaemia cells
June 8, 2016, The University of Manchester
Scientists identify drugs to target ‘Achilles heel’ of Chronic Myeloid Leukaemia cells
June 8, 2016, University of Glasgow
CML breakthrough thanks to Bloodwise funding
June 7, 2016, Bloodwise
Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo
February 28, 2014, Nature
p53 and c-Myc Are Critical Signaling Hubs That Maintain Chronic Myeloid Leukemia
November 15, 2013, Journal Blood
Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression
March 18, 2013, NCBI
Mutations in the p53 Tumor Suppressor Gene
April 2, 2011, NCBI
Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells.Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes
2005, Nature
c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells
April 27, 2000, Nature
