• Home
    • Leucémie myéloïde chronique
    • Leucemia Mieloide Crónica
  • CML Experts
    • Team of experts on CML who developed imatinib >
      • Dr. Elisabeth Buchdunger
      • Dr. Brian Druker
      • Dr. John Goldman
      • Dr. Carlo Gambacorti-Passerini
      • Dr. Nora C. Heisterkamp
      • Dr. David Hungerford
      • Dr. Nicholas Lydon
      • Dr. Alex Matter
      • Dr. Felix Mitelman
      • Dr. Peter C. Nowell
      • Dr. Moshe Talpaz
      • Dr. Janet D. Rowley
      • Dr. Charles Sawyers
      • Dr. Jürg Zimmermann
      • Dr. Owen Witte
    • Experts involved in developing dasatinib >
      • Dr. Jagabandhu Das
    • Experts involved in developing nilotinib
    • Other CML experts in America >
      • Other CML experts in Canada >
        • Dr. Sarit Assouline
        • Dr. Lambert Busque
        • Dr. Robert Delage
        • Dr. Connies Eaves
        • Dr. Josée Hébert
        • Dr. Luigina Mollica
        • Dr. Dennis Kim
        • Dr. Pierre Laneuville
        • Dr. Conrad Vincent Fernandez
        • Dr. Isabelle Bence-Bruckler
        • Dr. Jeffrey H Lipton
        • Dr. Mark Hnatiuk
      • Other CML experts in US >
        • Carolyn Blasdel, RN , FNP-BC, OCN
        • Rey Garcia, RN, BSN
        • PATRICIA JAKEL, RN, MN, AOCN
        • Dr. Ravi Bhatia
        • Dr. Jorge E. Cortes
        • Dr. Javier Pinilla-Ibarz
        • Dr. Catriona Jamieson
        • Dr. Arul Chinnaiyan
        • Dr. Michael Deininger
        • Dr. James D. Griffin
        • Dr. Franziska Michor
        • Dr. Frank Giles
        • Dr. Gabriella Hobbs
        • Dr. Elias J. Jabbour
        • Dr. Hagop Kantarjian
        • Dr. Harry P. Erba
        • Dr. Richard A. Larson
        • Dr. Alison Loren
        • Dr. Michael Mauro
        • Dr. Matt Kalaycio
        • Dr. Stephen D. Nimer
        • Dr. Ruben A. Mesa
        • Dr. Susan M. O'Brien
        • Dr. Jerald P. Radich
        • Dr. Ellen K. Ritchie
        • Dr. Karen Seiter
        • Dr. Kendra Sweet
        • Dr. Neil Shah
        • Dr. Richard T Silver
        • Dr. Richard Stone
        • Dr. Raoul Tibes
        • Dr. Sangmin Lee
        • Dr. Bin Zhang
      • Other CML experts in South America >
        • Dr. Michele Bianchini
        • Dra Beatriz Moiraghi
        • Dra. Carla Boquimpani
        • Dr Carolina Pavlovsky
    • Other CML Experts in Europe >
      • CML Expert in Belgium >
        • Pr Gregor Verhoef
      • CML expert in France >
        • Dr. François-Xavier Mahon
        • Dr Aude Charbonnier
        • Dr. Delphine Rea
        • Dr. Gabriel Etienne
        • Dr. Lawrence Legros
        • Dr. Marie-Joëlle Mozziconacci
        • Pr. Mauricette Michallet
        • Dr. François Guilhot
        • Dr Françoise Huguet
        • Dr. Stéphane Prost
        • Dr. Philippe Rousselot
        • Dr. Eliane Gluckman
        • Dr. Franck-Emmanuel Nicolini
      • CML expert in Italy >
        • Dr. Chiara Elena
        • Dr. Michele Baccarani
        • Dr. Giuseppe Saglio
      • CML expert in UK >
        • Dr. Jane Apperley
        • Dr. Stephen O'Brien
        • Dr. Georgios Nteliopoulos
        • Dr. Adam Mead
        • Dr. Tessa L Holyoake
      • CML expert in Germany >
        • Dr. Andreas Hochhaus
        • Dr Susanne Saussele
        • Dr. Martin Müller
      • CML expert in Portugal >
        • Dr. Antônio Medina de Almeida
      • CML expert in Spain >
        • Dr. Juan Luis Steegmann
      • CML expert in Netherlands >
        • Dr. Jeroen J.W.M. Janssen
      • CML expert in Sweden >
        • Dr. Johan Richter
      • CML expert in Czech Republic >
        • Dr. Hana Klamova
    • Other CML experts in Asia >
      • Dr. Charles Chuah
      • Dr. Goh Yeow Tee
      • Dr. Pankaj Malhotra
      • Dr. Uday Yanamandra
      • Dr. Hemant Malhotra
      • Dr. Kim Dong-Wook
    • Other CML experts in Africa >
      • Dr. Anthony Oyekunle
    • Other CML experts in Australia >
      • Dr. Ilaria Pagani
      • Dr. Susan Branford
      • Pr Tim Hughes
      • Dr. David T. Yeung
      • Dr. Liu Lu
      • Dr. Naranie Shanmuganathan
      • Dr. Anthony P Schwarer
  • Medical Concepts
    • Introduction to CML >
      • Precision medicine in chronic myeloid leukemia
      • Philadelphia chromosome
      • BCR-ABL Transcripts
      • Sokal, Hasford, and EUTOS scores
    • General concepts >
      • Blood
      • Bone Marrow
      • DNA
      • Stem Cells
      • Immune System >
        • Natural killer cell - NK
        • T Cells
      • Blood-Brain Barrier
    • Clinical Trials
    • Treatment response in CML
    • Resistance to treatment in CML >
      • Molecular monitoring in CML >
        • Polymerase Chain Reaction
        • Dr. Kary Bank Mullis
      • Non-adherence of CML patients
      • Sensitive detection of BCR-ABL1 mutations
      • JAK2 Gene
    • Donor lymphocyte infusion (DLI)
    • Interferon regulatory factor 8 (IRF8)
    • Myeloproliferative disorders (MPD) >
      • Introduction to CML
      • Essential Thrombocythemia (ET)
      • Myelofibrosis (MF)
      • Polycythemia Vera (PV)
    • Types of leukemia >
      • Atypical chronic myeloid leukemia
  • Medication
    • Hydroxyurea
    • Interferon Alpha
    • Gleevec (Imatinib) >
      • Generic Imatinib
    • Tasigna (Nilotinib) >
      • Generic nilotinib
    • Sprycel (Dasatinib) >
      • Generic Dasatinib
    • Bosulif (Bosutinib)
    • Iclusig (Ponatinib)
    • Supect (Radotinib)
    • ABL001 (Asciminib)
    • Synribo (Omacetaxine )
    • Jakafi (Ruxolitinib)
    • Flumatinib
    • (Bafetinib)
    • (Danusertib)
    • (Rebastinib)
    • BGB324
    • PF-114
    • NEV-801
    • BP1001
    • HQP1351 (Olverembatinib)
    • K0706
    • ​ S116836
    • Vidaza (Azacitidine)
  • Managing side effects
    • List of side effets >
      • Bone Pain
      • Depression
      • Eyes
      • Ear
      • Fatigue
      • Fluid Retention
      • Gastrointestinal system
      • Hair
      • Heart
      • Hepatotoxicity
      • Kidney
      • Muscle cramping
      • Peripheral Neuropathy in CML
      • Peripheral arterial disease in CML
      • Pleural effusion
      • Pulmonary arterial hypertension
      • Thyroid dysfunction
      • Skin
      • Weight gain
    • CML and Nutrition
    • Food and Drug Interactions
    • Living with CML and diabetes
    • CML and comorbidities
    • Psycho-Oncology
    • Complementary and Alternative Medicine >
      • Art Therapy >
        • Art Therapist
        • CMLer's portofolio
      • Music therapy >
        • YouTube creation by CMLer's family
        • Relaxing Music for Stress Relief. Calm Music for Meditation, Sleep, Healing Therapy, Spa
        • Debussy – Relaxing music - Clair de lune et autres...
        • Delicate music for the soul and LIFE, and birdsong soothes the nervous system.
        • Adagio for Strings (Samuel Barber)
        • Amélie Soundtrack ♥ Comptine d'Un Autre Été
      • Yoga
      • Physical Activity
      • Zootherapy
  • Patient Testimonials
    • 30 years and plus survivors >
      • Mark Popadick
      • Mary Sullivan
      • Tom Strodl
      • Dr. Robert Patenaude -E
      • Skip Duffe
    • 20 years and plus survivors >
      • Doug Jenson
      • Joannie Clements
      • Mel Mann
      • Kevin Williams
      • Rich Jones
      • Tanja Fajon
      • Tamera Simonson
      • Virginia Garner
    • 10 years and plus survivors >
      • Jan Geissler
      • Mary Jane Bertram
      • Pat Elliott
      • Tegan Kubler
      • Jo'story
      • Rob Shick
      • Gary Gonzales
      • Hans Loland
      • Drew Johnston
      • Erin Havel (Author)
      • Sohag
      • Erin Zammett Ruddy
      • Kayla Naton (Pregnancy)
      • Jean McGlynn
      • Tom Cleaver
    • New CMLers >
      • Skye Davidson
      • Amanda Steffy
      • Abbi Evans
      • Alyssa
      • Austin Granatowicz
      • Brown Dudley
      • Nigel
      • Katie
      • Kris
      • Ron Robbecke
    • Some celebrities >
      • How to get the password?
      • Alexa Score
      • Laura Boyd
      • Dr. Richard Rockefeller
      • Ryan O'Neal
      • Tim Holcomb
      • Doris Muramatsu
      • Charlie Schlatter
      • Kareem Abdul-Jabar
      • Kelvin Alston
      • Carlos Carrasco
      • Jason Blake
      • Brian Boyle
      • Roman Reigns
      • Rick Upchurch
    • Suzan Mc Namara and the petition
    • Bud Romine - the first patient
    • Other testimonials
    • Blogs >
      • Blog recently updated >
        • Access CML Drugs
        • Living with CML
        • Michelle D's Blog
        • Jon's Blog
        • Justin Ozuna's Blog
        • Trey's CML Leukemia Blog
      • Blog not recently updated >
        • CMKID's blog – Dislodging the bullet - 2012
        • CML Recovery - Stopping KTI -2011
        • Hans's Blog -2012
        • Elizabeth's Blog - my leukemia - 2013journey
        • Elizabeth's Blog - Heart of the rose -2011
        • Joe's Blog - 2012
        • Josh's Blog - 2014
        • Mannan's Blog -2014
        • Ian's Blog -2014
        • Matt's Blog - 2012
        • Matthew's Blog - 2014
        • Michelle's Blog -2012
        • Nayree's Blog -2011
        • Rob's Blog - 2011
  • Global News on CML
    • English - Latest CML News >
      • News -Archives 2019-2018
      • News - Archives 2017-2016
      • News Archives - 2015-2014
      • News-Archives -2013-2012
      • News - Archives 2011-2001
    • French (Français) - Dernières nouvelles
    • Spanish (Español)-Ultimas noticias
  • Links to other sites, forums and Facebook
    • Sites ( English and other languages)
    • Forums (English and other languages)
    • CML on Facebook (English and other languages)
    • CML on Twitter
    • Audio Podcast
  • Various topics
    • CML patients and the coronavirus
    • You’ve just been diagnosed
    • CML causes
    • Pronostic, life expectancy, quality of life, ..... in chronic myeloid leukemia
    • Increased Risk of Secondary Cancers with CML
    • Vaccination of CMLers
    • CML and pregnancy
    • Children with CML
    • Elderly patients with CML
    • Bone marrow transplant
    • Stem cells from umbilical cord blood
    • CML Blast Crisis treatment
    • Mutation T315I
    • Sports with CML
    • History of CML
    • CML Awareness Day
    • The movie "Dying to Survive"
  • Cure possible for CML?
    • Hematopoietic stem cell transplantation using single UM171-expanded cord blood
    • Combination of tyrosine kinase inhibitor with other medication >
      • Combinaison of hydroxychloroquine with tyrosine kinase inhibitor
      • Combination of ruxolitinib with tyrosine kinase inhibitor
      • Combination of miristen with tyrosine kinase inhibitor
      • Combination of pioglitazone with tyrosine kinase inhibitor
      • Combination of Inecalcitol with tyrosine kinase inhibitor
      • Combination of dasatinib plus Nivolumab
      • Combination of Pembrolizumab with tyrosine kinase inhibitor
      • Combination of interferon with tyrosine kinase inhibitor
      • Combination of Venetoclax with tyrosine kinase inhibitor
    • Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells
    • Inhibition of the protein Ezh2 can cure CML?
    • Inhibition of STAT5 in conjunction with standard TKI therapy
    • PROTAC-mediated Targeted Protein Degradation
    • CML vaccine
    • Can immunotherapy cure leukemia?
    • Could fasting cure chronic myeloid leukemia
    • Chimeric Antigen Receptor T-Cell Therapy
    • Can genetic sequencing help to cure leukemia?
    • Can the new drug CX-5461 cure leukemia?
    • CRISPR-Cas9 gene-editing technique
    • Presence of bcr abl fusion transcripts in healthy individua
    • Math could help cure leukemia
    • Natural Medicine >
      • Possible cure for CML in Fish Oil
      • Betel leaf may help fight CML
      • Feverfew extract (parthenolide)
      • Can dandelions kill cancer?
      • Can curcumin cure leukemia?
  • Treatment free remission(TFR)
    • The French trial called STIM (Stop Imatinib)
    • De-escalation of treatment
    • Tyrosine Kinase Inhibitor Withdrawal Syndrome in CML Patients
  • Educational videos
    • Educational videos (in English)
    • Educación de vídeos en español (in Spanish)
    • Vidéos pédagogiques en français (in French)
  • Educational events
  • CML Glossaries
  • Moral Support
    • Where to get help and support
    • Family support
    • Dances at the Cancer Research Centre
    • I Had Cancer: You are not alone
    • I’m A Doctor With Chronic Illness. Here Are 12 Things I Wish People Knew
    • 23 Nice Things You Can Do for Someone With Cancer
    • Stronger
    • The march toward healing
    • Be happy
  • Congresses, conferences, meetings ASH, ASCO, EHA ...
    • ASCO - American Society of Clinical Oncology >
      • ASCO 2020 - Chicago
      • ASCO 2019 - Chicago
      • ASCO 2018 - Chicago
      • ASCO 2017 - Chicago
      • ASCO 2016 - Chicago
      • ASCO 2015 - Chicago
      • ASCO 2014 - Chicago
      • ASCO 2013 - Chicago
      • ASCO 2012 - Chicago
      • ASCO 2011 - Chicago
      • ASCO 2010 - Chicago
    • ASH - American Society of Hematology >
      • ASH 2020 - Virtual
      • ASH 2019- Orlando
      • ASH 2018 - San Diego
      • ASH 2017 - Atlanta
      • ASH 2016 - San Diego
      • ASH 2015 - Orlando
      • ASH 2014 - San Francisco
      • ASH 2013 - New Orleans
      • ASH 2012 - Atlanta
      • ASH 2011 - San Diego
      • ASH 2010 - Orlando
      • ASH 2009 - New Orleans
    • BTG - Bridging the Gap >
      • BTG2019 - Fuzhou - China
      • BTG2018 - Seoul, Korea (South)
      • BTG 2011 - Singapore (Singapore)
    • CML & MPDs - UK National Meetings
    • CML Horizons >
      • CML Horizon 2019 - Lisbon - Portugal
      • CML Horizon 2018 -Warsaw (Pologna)
      • CML Horizon 2017- Frankfurt (Germany)
      • CML Horizon 2016 - Ljubljana (Slovenia)
      • CML Horizons 2015 - (Barcelona, Spain)
      • CML Horizons 2014 - ( Belgrade, Serbia)
      • CML Horizons 2013 - (Prague - Czech Republic)
      • CML Horizons 2012 - (Munich, Germany)
      • CML Horizons 2011 - (Amsterdam - The Netherlands)
    • EHA - European Hematology Association >
      • EHA 2020 - Frankfurt,Germany(
      • EHA 2019 - Amsterdam (Netherlands)
      • EHA 2018 - Stockholm(Sweden)
      • EHA 2017 - Madrid (Spain)
      • EHA2016-Copenhagen,(Denmark)
      • EHA 2015 - Vienne (Austria)
      • EHA 2014 - Milan (Italy)
      • EHA 2013 - Stockholm (Sweden)
      • EHA 2012 - Amsterdam (The Netherlands)
      • EHA 2011 - London (England)
      • EHA 2010 - Cascais (Portugal)
      • EHA 2009 - Berlin (Germany)
      • EHA 2008 - Copenhague (Danemark)
    • ESH - European School of Haematology >
      • ESH 2020 - Mandelieu-La Napoule, -France
      • ESH 2019 - Bordeaux - France
      • ESH 2016 - Houston - USA
      • ESH 2015 - Estoril - Portugal
      • ESH 2014 - Philadelphia
  • Professionnel help and literature
    • Dr. Siddhartha Mukherjee
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Chronic Myeloid Leukemia

Chronic Myeloid Leukemia (CML) and pregnancy

 
Important notice: All decisions made regarding treatments for CML in case of pregnancy should be made after consultation with  qualified doctors (CML specialist and obstetrician). The information and opinions expressed on this website are intended for informational purposes only.
SITES

Fertility, Pregnancy and Breast Feeding
by  The National CML Society

A Global Gleevec/Glivec and Tasigna Pregnancy Exposure Registry
by  ClinicalTrials.gov
FORUMS

CML and Pregnancy (CML expert forum)
by iCMLf

CML and pregnancy ( Forum on cmlsupport)
CML during and after pregnancy (Forum on cmlsupport)
 
CML Mamas - Pregnancy and Parenting with CML  (Faceboo
k)   NEW


VIDEOS


Surrogacy: 'It was too dangerous for me to give birth'
January  9, 2020,
 BBC News

Pregnancy in patients with cancer – perspectives from cancer survivors
July 25, 2017, VJHemOnc – Video Journal of Hematological Oncology 

Sneak peek: Elle Halliwell | Sunday on 60 Minutes
May 11, 2017, 60 Minutes Australia

60 Minutes Australia: Impossible Choice (2016)
April 26, 2017, 60 Minutes Australia

Being diagnosed with CML when you're pregnant (Professor Jane Apperley)
September 7, 2015, Bloodwise


Becoming pregnant while you're being treated for CML
September 7, 2015, Bloodwise


Kayla Nation: Young Mother with CML Perseveres
January 9, 2012, Patient Power

Hans Loland: A CML Diagnosis and a Miracle Baby
January 3, 2012, Patient Power
LITERATURE

A Mother's Choice       NEW
April 24, 2018, Elle Halliwell.
ARTICLES

Pregnancy outcomes in patients treated with bosutinib
May 29, 2020, PubMed

TKI Therapy Interruption Recommended for Pregnant Patients With CML
February 26, 2020, Oncology Learning Network


Successful Planned Pregnancy through Vitrified-Warmed Embryo Transfer in a Woman with Chronic Myeloid Leukemia: Case Report and Literature Review
January 12, 2020. 
PubMed

Living a happy life with leukaemia
December 25, 2019, 
BBC News

Study Finds Women With Rare Bone Marrow Cancer Can Still Have Safe Childbirth
June 14, 2019, docwire
​

Conception, Pregnancy Possible During TKI Therapy for Chronic Myeloid Leukemia
​December 13, 2018,  Oncology Nurse Advisor

If You're Struggling To Become A Mother, This Is For You
May 13, 2018, MindBodyGreen

'Getting pregnant could kill me': Roz Purcell's sister Rachel reveals struggle with chronic myeloid leukaemia
April 30, 2018,  Irish Mirror
​
Northern Ireland mother who bravely delayed cancer treatment until her children were born
April 26, 2018, Belfast Telegraph

​
Experience with dasatinib and nilotinib use in pregnancy
February 17, 2017,  Sage Journals

Could Switching to Interferon Avoid an Abnormal Ovarian Response in CML?
January 17, 2018, Cancer Therapy Advisor


Elle Halliwell reveals how she is coming to terms with having leukaemia and being pregnant with her first child
August 25, 2016, The Daily Telegraph

Loss of Pregnancy in a Patient with Chronic Myeloid Leukemia During Treatment with Nilotinib
March 2016, Journal of Hematology Oncology Pharmacy
  
Introduction of a Treatment Approach for Chronic Myeloid Leukemia and Pregnancy Considering Leukemic Burden and Pregnancy Terms
December 3, 2015, Journal Blood
 
Is pregnancy wise after 12-year chemotherapy of chronic myeloid leukemia woman?
October, 2015, Journal of Cancer Metastasis and Treatment

A female chronic myeloid leukemia patient who gave birth after stopping imatinib intentionally but who maintained a major molecular response with interferon
2015, Europe PMC

Discontinuation of Tyrosine Kinase Inhibitors and Pregnancy for Female Patients with Chronic Myeloid Leukemia

July 8, 2014, SciMedCentral
 
Tyrosine Kinase Inhibitors and Pregnancy
April 7, 2014, NCBI

Chronic myeloid leukemia with pregnancy: Successful management of pregnancy and delivery with hydroxyurea and imatinib continued till delivery
October 8, 2013,  Journal of Cancer Research and Therapeutics

Twin pregnancy and childbirth after  reduced-intensity conditioning allogeneic haematopoietic stem cell transplantation combined with imatinib mesylate for chronic myeloid leukaemia: case report and literature review
September 26, 2013,  CBMTG

Two Successful Successive Pregnancies in a Woman with CML Treated with Dasatinib and Temporary Peg-Interferon
June 2013, Journal of US-China Medical Science

Planned pregnancy in a chronic myeloid leukemia patient in molecular remission.
May 16, 2012, PubLMed

Planned Pregnancy  in CML Patient in Molecular Remission
March 6, 2012, Hindawi

Miracle mum-to-be
April 27, 2012, Sunshine Coast Daily
​Planned pregnancy in a Chronic Myeloid Leukemia patient in molecular remission
March 3, 2012, Ispub

Hematologic Cancers in Pregnancy Pose Substantial Risks

February 14, 2012, Medscape


TKIs and the treatment of CML in pregnant women
October 25, 2011,  HemOnc Today

Two successful pregnancies in a woman with chronic myeloid leukemia exposed to nilotinib during the first trimester of her second pregnancy: case study
October 6, 2009, Journal of Hematology and Oncology

Planned Pregnancy for a Patient with Chronic Myeloid Leukemia
2009, Internet Scientific Publications

Successful delivery after planned discontinuation of imatinib in a patient with chronic myeloid leukemia.
2009, PublMed

The effects of imatinib on pregnancy outcome
June 15, 2008, Journal Blood

Women Taking Imatinib Should Avoid Pregnancy
March 12, 2008, Medscape

Imatinib and Pregnancy
June 2006, Journal of Clinical Oncology

Pregnancy Among Patients With Chronic Myeloid Leukemia Treated With Imatinib
March 2006, Journal of Clinical Oncology

Pregnancy on imatinib: fatal outcome with meningocele
2005,  Annals of Oncology. Oxford Journals

Successful Pregnancy and Delivery in a Patient with Chronic Myelogenous Leukemia (CML), and Management of CML with Leukapheresis during Pregnancy: a Case Report and Review of the Literature
March 2004, Japanese Journal of Clinical Oncology
                          

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