Iclusig® (Ponatinib) - Chronic Myeloid Leukemia - CML
SITES
Iclusig®(Ponatinib) - Ariad
FORUMS
Ponatinib by LLS Group discussion
Iclusib® by CML2 support group
Ponatinib on Facebook
BLOGS
Hans’s Blog
CLINICAL TRIALS
Ponatinib for CML Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL) (PACE)
Expanded Access Program of Ponatinib
A Study Comparing Ponatinib and Nilotinib in Patients With Chronic Myeloid Leukemia (OPTIC-2L)
Ponatinib for CML Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL) (PACE)
Expanded Access Program of Ponatinib
A Study Comparing Ponatinib and Nilotinib in Patients With Chronic Myeloid Leukemia (OPTIC-2L)
VIDEOS
Using ponatinib to treat highly resistant chronic myeloid leukemia, results from a Phase I trial
January 10, 2017, VJHemOnc
Management of Thrombosis Risk with Ponatinib and other TKIs for CML?
May 15, 2015, ImedexCME
Epic:Phase 3 Trial of Ponatinib Compared with Imatinib in Newly Diagnosed Chronic Myeloid Leukemia
February 16, 2015, Oncology.TV
More on Ponatinib and Next Steps - Harry Erba, MD
November 7, 2013, NationalCMLSociety
Considerations for Patients Taking Ponatinib - Michael Mauro, MD
November 5, 2013, NationalCMLSociety·
Study Brings Positive Results For the Most Resistant Types of CML
December 12, 2012, Patient Power
Dr. Jorge Cortes Discusses the Ponatinib Ph+All and CML Evaluation (PACE) Trial
June 14, 2012, OncLive
ARIAD: Xiaotian Zhu on Ponatinib
April 3, 2012, Executive video
Dr. Jorges Cortes: ASH2011 - Two New Winners for CML?
December 23, 2011, Medscape News Today
ARTICLES
Rechallenge of ponatinib in chronic myeloid leukaemia after hepatotoxicity
April 2019, Hong Kong Medical Journal
Pre- and post-transplant ponatinib for a patient with acute megakaryoblastic blast phase chronic myeloid leukemia with T315I mutation who underwent allogeneic hematopoietic stem cell transplantation
March 16, 2019, PubMed
Ponatinib Tops Bosutinib for Third-Line Treatment of CML in a Comparative Analysis
October 15, 2018, Cancer Therapy Advisor
Real-life Experience With Ponatinib in Chronic Myeloid Leukemia: A Multicenter Observational Study
May 7, 2018, PubMed
Analyst 'would not be surprised' to see Takeda retry Iclusig in first-line CML
March 25, 2018, The Pharma Letter
Takeda Announces Publication of Final Data from ICLUSIG® (ponatinib) Pivotal Phase 2 PACE Trial in Blood
March 22, 2018, Boston Business Journal
Publication of Final Data from ICLUSIG (ponatinib) Pivotal Phase 2 PACE Trial
March 22, 2018, Drug Discovery & Development
Ponatinib Maintains Benefit in Chronic-Phase CML at 5 Years
March 22, 2018, OncLive
Ponatinib Shows Promise for Rare Ovarian Cancer Type that Affects Young Women
March 8, 2018, Oncology Nursing News
Efficacy and Safety of Ponatinib in Chronic Phase-Chronic Myeloid Leukemia (CP-CML) According to the Extent of Treatment with Prior Tyrosine Kinase Inhibitors (TKIs): Final (5-Year) Results of the PACE Study
December 2017, ASH 2017
A Conservative Tailoring of Ponatinib Dose in Chronic Myeloid Leukemia Patients Can Diminish Adverse Events While Maintaining Efficacy
December 2017, ASH 2017
Arterial Occlusive Events (AOEs) in the Phase 2 Ponatinib PACE Trial: 5-Year Update in Heavily Treated Patients (Pts) with Chronic-Phase Chronic Myeloid Leukemia (CP-CML)
December 2017, ASH 2017
A Real Life Evaluation of Efficacy and Safety of Ponatinib Therapy in CML Patients
December 2017, ASH 2017
Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting
October 2017, PublMed
Ponatinib: Black Box Warning and Drug Interactions
January 17, 2017, Cancer Therapy Advisor
The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib
April 14, 2016, NCBI
Ponatinib and Cardiovascular Complications
December 4, 2016, ASH 2016
Ponatinib in Chronic-Phase Chronic Myeloid Leukemia Patients: Final Report from a Phase 1 Trial
December 4, 2016, ASH 2016
Long-Term Follow-up of the Efficacy and Safety of Ponatinib in Philadelphia Chromosome-Positive Leukemia
Patients with the T315I Mutation
December 4, 2016, ASH 2016
Imatinib as Second-Line Therapy, Ameliorates or Maintains Molecular Responses Obtained with Ponatinib First-Line in Chronic Phase CML Patients
December 3, 2016, ASH 2016
Ponatinib Approved for CP-CML Not Indicated for Prior TKI
December 1, 2016, Cancer Therapy Advisor
FDA Fully Approves Iclusig for Chronic Myeloid Leukemia
November 29, 2016, Rare Disease Report
Response Rate Similar Between Low- and Standard-dose Ponatinib
September 23, 2016, Cancer Therapy Advisor
Efficacy and safety of second-line ponatinib after failure of a single previous tyrosine kinase inhibitor for chronic myeloid leukemia patients in chronic phase
June 2016, Haematologica
Vascular Events Remain Problem for Ponatinib in CML
Apr 22, 2016, Cancer Network
The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib
April 14, 2016, NCBI
Ponatinib vs Allogeneic SCT Promising for T315I Mutation-positive CP-CML
January 11, 2016, Cancertherapyadvisor
ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib from Phase 2 Pace Clinical Trial
June 12, 2014, Business Wire
Four-year minimum follow-up of ongoing patients (pts) with chronic-phase chronic myeloid leukemia (CP-CML) in a phase 1 trial of ponatinib (PON)
June 2015, 2015 ASCO Annual Meeting
Elevated blood pressure (BP) and adverse events (AEs) of hypertension (HTN) in ponatinib (PON) leukemia trials.
June 2015, 2015 ASCO Annual Meeting
Efficacy and safety of ponatinib in heavily pretreated leukemia patients in the PACE trial: 3-year results.
June 2015, 2015 ASCO Annual Meeting
Long-term Bosutinib in patients with chronic phase CML after prior imatinib failure
June 2015, EHA 2015
Ponatinib efficacy and safety in heavily pretreated leukemia patients: 3-year results of the Pace trial
June 2015, EHA 2015
Ponatinib efficacy and safety in heavily pretreated leukemia patients: 3-year results of the Pace trial
June 2015, EHA 2015
Long-term follow-up of ponatinib effivacy and safety in patients (PTS) with the T315I mutation in the phase 1 and phase 2(pace) trials.
June 2015, EHA 2015
Elavated Blood Pressure ans adverse events of hypertension in phase 1,2 and 3 trials of ponationib in leukemia
June 2015, EHA 2015
T315I clone selectioin in a PH+ All patient under maintenance Ponatinib
June 2015, EHA 2015
Hematologic safety data of single-agent ponatinib from a phase I and phase II trial in Philadelphia chromosome-positive (Ph+) CML/ALL patients
June 2, 2014, 2014 ASCO Annual Meeting
Longer-term follow up of a phase 1 study of ponatinib in patients (pts) with Philadelphia chromosome-positive (Ph+) leukemiasLonger-term follow up of a phase 1 study of ponatinib in patients (pts) with Philadelphia chromosome-positive (Ph+) leukemias
June 2, 2014, 2014 ASCO Annual Meeting
EPIC: A phase III trial of ponatinib (PON) versus imatinib (IM) in patients (pts) with newly diagnosed CP-CML
May 31, 2014, 2014 ASCO Annual Meeting
ARIAD Announces Commercial Agreement for Iclusig (Ponatinib) in Australia
January 28, 2014, Business Wire
Advocates Lobby for Continued Access to Ponatinib in US
November 26, 2013, Medscape
Patients' advocates press FDA to retain lifesaving drugs (Iclusig)
November 24, 2013, Boston Globe
Ariad jumps on European drug action
November 23, 2013, Boston Globe
European Medicines Agency recommends changes in use of leukaemia medicine Iclusig (ponatinib) in order to minimise
risk of blood clots
November 22, 2013, European Medicine Agency
Ponatinib demonstrated activity in patients with CML, Ph+ALL
November 21, 2013, HemOnctoday
PRAC updates on the risks of serious vascular occlusive events associated with cancer medicine Iclusig
November 8, 2013, European Medicines Agency
FDA provides steps to obtain ponatinib following suspension
November 6, 2013, The Oncology Report
Doctors Fear Losing Leukemia Drug Deemed Risky
November 1, 2013, New York Times
The Leukemia & Lymphoma Society Issues Statement Regarding the Status of Iclusig
November 1, 2013, DigitalJournal.com
Ariad Suspends Sales of Cancer Pill Iclusig
October 31, 2013, abcNews
Serious Danger of Blood Clots Halts Sale of Leukemia Drug
October 31, 2013, New York Times
Genetic details of leukemia resistance
October 31, 2013, Oncology Nurse Advisor
Ariad announces discontinuation of a trial for its leukemia drug
October 18, 2013, boston.com
Girard Gibbs LLP Announces Investigation of ARIAD (ARIA) Pharmaceuticals, Inc.
Oct 18, 2013, MarketWatch
Ariad Halts Iclusig Trial; Shares Plunge Over 38%
Oct 18, 2013, NASDAQ
Ariad crushed (again) after PhIII Iclusig trial is shuttered on blood clot fears
October 18, 2013, FierceBiotech
Ariad Stops Phase 3 Epic Trial Of Iclusig In Patients With Newly Diagnosed CML
October 18, 2013, RTT News
Inclusig (Ponatinib): Drug Safety Communication - Increased Reports Of Serious Blood Clots In Arteries And
Veins
October 11, 2013, FDA
Safety Concerns Halt Ponatinib Development
October 9, 2013, Onc LIve
Ariad's Nasty Surprise Gives The Sellside Pause For Thought
October 9, 2013, Seeking Alpha
Ponatinib—A Step Forward in Overcoming Resistance in Chronic Myeloid Leukemia
August 5, 2013, Clinical cancer Research
Effects of food on the pharmacokinetics of ponatinib in healthy subjects.
July 25, 2013, PublMed
“Borne Out of Necessity and Data”: Conquering Mutations in Leukemia
February 6, 2013, PLOS Blog
New TKI Ponatinib Effective in Resistant CML
February 2013, Clinical Oncology News
Ponatinib Could Herald “Revolution”in CML Treatment
December 20, 2012, OncLive
Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias
November 29, 2012, The New England Journal of Medicine
F.D.A. Gives Early Approval to Drug for Rare Leukemia
December 14, 2012, The New York Times
OHSU-developed ponatinib wins FDA approval
December 14, 2012, Portland Business Journal
FDA grants approval for potential ‘blockbuster’ leukemia drug made by Cambridge-based Ariad
December 14, 2012, Boston.com
ARIAD Announces Accelerated Approval by FDA of Iclusig (Ponatinib) for Patients with CML and Ph+ ALL Resistant or
Intolerant to Prior Tyrosine Kinase Inhibitor Therapy
December 14, 2012, Ariad
FDA Approves Ariad Pharma Leukemia Drug
December 14, 2012, The Street
Ponatinib offers new hope in drug-resistant leukemia
December 5, 2012 , News-Medical.net
Chronic Myeloid Leukemia Mutation Thwarted By Ponatinib
December 2, 2012, Science 2.0
Data Published on ARIAD Candidate - Analyst Blog
November 30, 2012, Nasdaq
In CML, Next-Generation TKIs Aim to Boost Outcomes
November 30, 2012, Onc LIve
Ponatinib - Cancer pill targets previously impenetrable disease-causing gene mutation in leukemia patients
November 29, 2012, OHSU
Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia
November 29, 2012, News Medical
Ponatinib for Chronic Myeloid Leukemia
November 29, 2012, The New England Journal of Medicine
Ponatinib acts against the most resistant types of chronic myeloid leukemia
November 28, 2012, Science Codex
Ponatinib Acts Against the Most Resistant Types of Chronic Myeloid Leukemia
November 28, 2012, Science Daily
PropThink: Management says Ariad is Well-Prepared for Ponatinib Launch
November 7, 2012, Reuters
FDA Agrees to Speed Review of Ariad Drug
October 25, 2012, DailyFinance
PropThink: ARIAD Building an Oncology Business Around Discovery, Development, and Commercialization
October 4, 2012, Reuters
Ariad Pharmaceuticals: Ponatinib Approval Anticipated In Second-Line CML
October 1, 2012, Seeking Alpha
ARIAD Announces Submission of Marketing Authorization Application for Ponatinib to the European Medicines Agency
August. 30, 2012, ARIAD Pharmaceuticals, Inc.
Ariad seeks approval for leukemia drug in Europe
August 30, 2012, MHT
Ariad Pharmaceuticals Gearing Up For Ponatinib's Approval
August 29, 2012, Seeking Alpha
ARIAD Pharma initiates phase I/II trial of ponatinib in Japan
August 22, 2012, Pharmabiz.com
Accelerated FDA Approval for CML Drug Ponatinib Sought
August 9, 2012, Cancer Network
Ponatinib Achieves Primary Endpoints in CML Subtypes
August 8, 2012, OncLive
Ariad Prepares for Early Launch of CML Drug Ponatinib
August 6, 2012, Oncology Stat
Ariad speeds targeted leukemia drug to FDA in race for key approval
July 31, 2012, FierceBiotech
Ariad Pharma ANNOUNCES Phase 3 Trial and 4 Stocks Hitting 52-Week Highs
July 28, 2012, Wall St . Cheqt Sheet
Platelet dysfunction associated with ponatinib, a new pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to multiple tyrosine kinase inhibitor therapy
April 24, 2012, Haematologica
Rechallenge of ponatinib in chronic myeloid leukaemia after hepatotoxicity
April 2019, Hong Kong Medical Journal
Pre- and post-transplant ponatinib for a patient with acute megakaryoblastic blast phase chronic myeloid leukemia with T315I mutation who underwent allogeneic hematopoietic stem cell transplantation
March 16, 2019, PubMed
Ponatinib Tops Bosutinib for Third-Line Treatment of CML in a Comparative Analysis
October 15, 2018, Cancer Therapy Advisor
Real-life Experience With Ponatinib in Chronic Myeloid Leukemia: A Multicenter Observational Study
May 7, 2018, PubMed
Analyst 'would not be surprised' to see Takeda retry Iclusig in first-line CML
March 25, 2018, The Pharma Letter
Takeda Announces Publication of Final Data from ICLUSIG® (ponatinib) Pivotal Phase 2 PACE Trial in Blood
March 22, 2018, Boston Business Journal
Publication of Final Data from ICLUSIG (ponatinib) Pivotal Phase 2 PACE Trial
March 22, 2018, Drug Discovery & Development
Ponatinib Maintains Benefit in Chronic-Phase CML at 5 Years
March 22, 2018, OncLive
Ponatinib Shows Promise for Rare Ovarian Cancer Type that Affects Young Women
March 8, 2018, Oncology Nursing News
Efficacy and Safety of Ponatinib in Chronic Phase-Chronic Myeloid Leukemia (CP-CML) According to the Extent of Treatment with Prior Tyrosine Kinase Inhibitors (TKIs): Final (5-Year) Results of the PACE Study
December 2017, ASH 2017
A Conservative Tailoring of Ponatinib Dose in Chronic Myeloid Leukemia Patients Can Diminish Adverse Events While Maintaining Efficacy
December 2017, ASH 2017
Arterial Occlusive Events (AOEs) in the Phase 2 Ponatinib PACE Trial: 5-Year Update in Heavily Treated Patients (Pts) with Chronic-Phase Chronic Myeloid Leukemia (CP-CML)
December 2017, ASH 2017
A Real Life Evaluation of Efficacy and Safety of Ponatinib Therapy in CML Patients
December 2017, ASH 2017
Life after ponatinib failure: outcomes of chronic and accelerated phase CML patients who discontinued ponatinib in the salvage setting
October 2017, PublMed
Ponatinib: Black Box Warning and Drug Interactions
January 17, 2017, Cancer Therapy Advisor
The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib
April 14, 2016, NCBI
Ponatinib and Cardiovascular Complications
December 4, 2016, ASH 2016
Ponatinib in Chronic-Phase Chronic Myeloid Leukemia Patients: Final Report from a Phase 1 Trial
December 4, 2016, ASH 2016
Long-Term Follow-up of the Efficacy and Safety of Ponatinib in Philadelphia Chromosome-Positive Leukemia
Patients with the T315I Mutation
December 4, 2016, ASH 2016
Imatinib as Second-Line Therapy, Ameliorates or Maintains Molecular Responses Obtained with Ponatinib First-Line in Chronic Phase CML Patients
December 3, 2016, ASH 2016
Ponatinib Approved for CP-CML Not Indicated for Prior TKI
December 1, 2016, Cancer Therapy Advisor
FDA Fully Approves Iclusig for Chronic Myeloid Leukemia
November 29, 2016, Rare Disease Report
Response Rate Similar Between Low- and Standard-dose Ponatinib
September 23, 2016, Cancer Therapy Advisor
Efficacy and safety of second-line ponatinib after failure of a single previous tyrosine kinase inhibitor for chronic myeloid leukemia patients in chronic phase
June 2016, Haematologica
Vascular Events Remain Problem for Ponatinib in CML
Apr 22, 2016, Cancer Network
The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib
April 14, 2016, NCBI
Ponatinib vs Allogeneic SCT Promising for T315I Mutation-positive CP-CML
January 11, 2016, Cancertherapyadvisor
ARIAD Announces Long-Term Safety and Efficacy Data of Ponatinib from Phase 2 Pace Clinical Trial
June 12, 2014, Business Wire
Four-year minimum follow-up of ongoing patients (pts) with chronic-phase chronic myeloid leukemia (CP-CML) in a phase 1 trial of ponatinib (PON)
June 2015, 2015 ASCO Annual Meeting
Elevated blood pressure (BP) and adverse events (AEs) of hypertension (HTN) in ponatinib (PON) leukemia trials.
June 2015, 2015 ASCO Annual Meeting
Efficacy and safety of ponatinib in heavily pretreated leukemia patients in the PACE trial: 3-year results.
June 2015, 2015 ASCO Annual Meeting
Long-term Bosutinib in patients with chronic phase CML after prior imatinib failure
June 2015, EHA 2015
Ponatinib efficacy and safety in heavily pretreated leukemia patients: 3-year results of the Pace trial
June 2015, EHA 2015
Ponatinib efficacy and safety in heavily pretreated leukemia patients: 3-year results of the Pace trial
June 2015, EHA 2015
Long-term follow-up of ponatinib effivacy and safety in patients (PTS) with the T315I mutation in the phase 1 and phase 2(pace) trials.
June 2015, EHA 2015
Elavated Blood Pressure ans adverse events of hypertension in phase 1,2 and 3 trials of ponationib in leukemia
June 2015, EHA 2015
T315I clone selectioin in a PH+ All patient under maintenance Ponatinib
June 2015, EHA 2015
Hematologic safety data of single-agent ponatinib from a phase I and phase II trial in Philadelphia chromosome-positive (Ph+) CML/ALL patients
June 2, 2014, 2014 ASCO Annual Meeting
Longer-term follow up of a phase 1 study of ponatinib in patients (pts) with Philadelphia chromosome-positive (Ph+) leukemiasLonger-term follow up of a phase 1 study of ponatinib in patients (pts) with Philadelphia chromosome-positive (Ph+) leukemias
June 2, 2014, 2014 ASCO Annual Meeting
EPIC: A phase III trial of ponatinib (PON) versus imatinib (IM) in patients (pts) with newly diagnosed CP-CML
May 31, 2014, 2014 ASCO Annual Meeting
ARIAD Announces Commercial Agreement for Iclusig (Ponatinib) in Australia
January 28, 2014, Business Wire
Advocates Lobby for Continued Access to Ponatinib in US
November 26, 2013, Medscape
Patients' advocates press FDA to retain lifesaving drugs (Iclusig)
November 24, 2013, Boston Globe
Ariad jumps on European drug action
November 23, 2013, Boston Globe
European Medicines Agency recommends changes in use of leukaemia medicine Iclusig (ponatinib) in order to minimise
risk of blood clots
November 22, 2013, European Medicine Agency
Ponatinib demonstrated activity in patients with CML, Ph+ALL
November 21, 2013, HemOnctoday
PRAC updates on the risks of serious vascular occlusive events associated with cancer medicine Iclusig
November 8, 2013, European Medicines Agency
FDA provides steps to obtain ponatinib following suspension
November 6, 2013, The Oncology Report
Doctors Fear Losing Leukemia Drug Deemed Risky
November 1, 2013, New York Times
The Leukemia & Lymphoma Society Issues Statement Regarding the Status of Iclusig
November 1, 2013, DigitalJournal.com
Ariad Suspends Sales of Cancer Pill Iclusig
October 31, 2013, abcNews
Serious Danger of Blood Clots Halts Sale of Leukemia Drug
October 31, 2013, New York Times
Genetic details of leukemia resistance
October 31, 2013, Oncology Nurse Advisor
Ariad announces discontinuation of a trial for its leukemia drug
October 18, 2013, boston.com
Girard Gibbs LLP Announces Investigation of ARIAD (ARIA) Pharmaceuticals, Inc.
Oct 18, 2013, MarketWatch
Ariad Halts Iclusig Trial; Shares Plunge Over 38%
Oct 18, 2013, NASDAQ
Ariad crushed (again) after PhIII Iclusig trial is shuttered on blood clot fears
October 18, 2013, FierceBiotech
Ariad Stops Phase 3 Epic Trial Of Iclusig In Patients With Newly Diagnosed CML
October 18, 2013, RTT News
Inclusig (Ponatinib): Drug Safety Communication - Increased Reports Of Serious Blood Clots In Arteries And
Veins
October 11, 2013, FDA
Safety Concerns Halt Ponatinib Development
October 9, 2013, Onc LIve
Ariad's Nasty Surprise Gives The Sellside Pause For Thought
October 9, 2013, Seeking Alpha
Ponatinib—A Step Forward in Overcoming Resistance in Chronic Myeloid Leukemia
August 5, 2013, Clinical cancer Research
Effects of food on the pharmacokinetics of ponatinib in healthy subjects.
July 25, 2013, PublMed
“Borne Out of Necessity and Data”: Conquering Mutations in Leukemia
February 6, 2013, PLOS Blog
New TKI Ponatinib Effective in Resistant CML
February 2013, Clinical Oncology News
Ponatinib Could Herald “Revolution”in CML Treatment
December 20, 2012, OncLive
Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias
November 29, 2012, The New England Journal of Medicine
F.D.A. Gives Early Approval to Drug for Rare Leukemia
December 14, 2012, The New York Times
OHSU-developed ponatinib wins FDA approval
December 14, 2012, Portland Business Journal
FDA grants approval for potential ‘blockbuster’ leukemia drug made by Cambridge-based Ariad
December 14, 2012, Boston.com
ARIAD Announces Accelerated Approval by FDA of Iclusig (Ponatinib) for Patients with CML and Ph+ ALL Resistant or
Intolerant to Prior Tyrosine Kinase Inhibitor Therapy
December 14, 2012, Ariad
FDA Approves Ariad Pharma Leukemia Drug
December 14, 2012, The Street
Ponatinib offers new hope in drug-resistant leukemia
December 5, 2012 , News-Medical.net
Chronic Myeloid Leukemia Mutation Thwarted By Ponatinib
December 2, 2012, Science 2.0
Data Published on ARIAD Candidate - Analyst Blog
November 30, 2012, Nasdaq
In CML, Next-Generation TKIs Aim to Boost Outcomes
November 30, 2012, Onc LIve
Ponatinib - Cancer pill targets previously impenetrable disease-causing gene mutation in leukemia patients
November 29, 2012, OHSU
Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia
November 29, 2012, News Medical
Ponatinib for Chronic Myeloid Leukemia
November 29, 2012, The New England Journal of Medicine
Ponatinib acts against the most resistant types of chronic myeloid leukemia
November 28, 2012, Science Codex
Ponatinib Acts Against the Most Resistant Types of Chronic Myeloid Leukemia
November 28, 2012, Science Daily
PropThink: Management says Ariad is Well-Prepared for Ponatinib Launch
November 7, 2012, Reuters
FDA Agrees to Speed Review of Ariad Drug
October 25, 2012, DailyFinance
PropThink: ARIAD Building an Oncology Business Around Discovery, Development, and Commercialization
October 4, 2012, Reuters
Ariad Pharmaceuticals: Ponatinib Approval Anticipated In Second-Line CML
October 1, 2012, Seeking Alpha
ARIAD Announces Submission of Marketing Authorization Application for Ponatinib to the European Medicines Agency
August. 30, 2012, ARIAD Pharmaceuticals, Inc.
Ariad seeks approval for leukemia drug in Europe
August 30, 2012, MHT
Ariad Pharmaceuticals Gearing Up For Ponatinib's Approval
August 29, 2012, Seeking Alpha
ARIAD Pharma initiates phase I/II trial of ponatinib in Japan
August 22, 2012, Pharmabiz.com
Accelerated FDA Approval for CML Drug Ponatinib Sought
August 9, 2012, Cancer Network
Ponatinib Achieves Primary Endpoints in CML Subtypes
August 8, 2012, OncLive
Ariad Prepares for Early Launch of CML Drug Ponatinib
August 6, 2012, Oncology Stat
Ariad speeds targeted leukemia drug to FDA in race for key approval
July 31, 2012, FierceBiotech
Ariad Pharma ANNOUNCES Phase 3 Trial and 4 Stocks Hitting 52-Week Highs
July 28, 2012, Wall St . Cheqt Sheet
Platelet dysfunction associated with ponatinib, a new pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to multiple tyrosine kinase inhibitor therapy
April 24, 2012, Haematologica
Ariad Pharmaceuticals Still Might Have Upside
December 21, 2011, Investor Place
Ariad's ponatinib takes center stage with promising pivotal leukemia data
December 12, 2011, Fierce Biotech
Drug For Chronic Myeloid Leukemia To Be Out Soon
December 12, 2011, TopNews
Initial Findings from the PACE trial: A Pivotal Phase 2 Study of Ponatinib in Patients with CML and Ph+All
Resistant or Intolerant or Dasatinib or Nilotinib, or with the T315I Mutation
December 2, 2011, Ariad
Ariad Pharma: Early Efficacy, Safety of Leukemia Drug 'Striking'
November 7, 2011, The Street
ARIAD Presents New Preclinical Data On Ponatinib In Solid Tumors, Demonstrating Inhibition Of All FGF Receptor Kinases
April 6, 2011, Medical News Today
Phase I Trial Shows Ponatinib May Thwart Most Resistant CML
December 16, 2010, MD Anderson Cancer Center - Department of Leukemia
Updated Phase 1 study data of ponatinib in patients with refractory CML, Ph+ ALL presented at ASH
December 6, 2010 , News medical
Novel CML Drug Active After Failures of Imatinib, Dasatinib, and Nilotinib
December 6, 2010, Oncology Stat
Phase I Trial Indicates Ponatinib May Thwart Most Resistant CML
December 2010, Drugs.com
ARIAD Announces Initiation Of Ponatinib (AP24534) Pivotal Trial In Drug-Resistant Or Intolerant Chronic Myeloid Leukemia
September 2010, Medical News Today
Phase 2 trial of ponatinib for the treatment of chronic myeloid leukemia (CML) and Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL)
September 2010, MPR
December 21, 2011, Investor Place
Ariad's ponatinib takes center stage with promising pivotal leukemia data
December 12, 2011, Fierce Biotech
Drug For Chronic Myeloid Leukemia To Be Out Soon
December 12, 2011, TopNews
Initial Findings from the PACE trial: A Pivotal Phase 2 Study of Ponatinib in Patients with CML and Ph+All
Resistant or Intolerant or Dasatinib or Nilotinib, or with the T315I Mutation
December 2, 2011, Ariad
Ariad Pharma: Early Efficacy, Safety of Leukemia Drug 'Striking'
November 7, 2011, The Street
ARIAD Presents New Preclinical Data On Ponatinib In Solid Tumors, Demonstrating Inhibition Of All FGF Receptor Kinases
April 6, 2011, Medical News Today
Phase I Trial Shows Ponatinib May Thwart Most Resistant CML
December 16, 2010, MD Anderson Cancer Center - Department of Leukemia
Updated Phase 1 study data of ponatinib in patients with refractory CML, Ph+ ALL presented at ASH
December 6, 2010 , News medical
Novel CML Drug Active After Failures of Imatinib, Dasatinib, and Nilotinib
December 6, 2010, Oncology Stat
Phase I Trial Indicates Ponatinib May Thwart Most Resistant CML
December 2010, Drugs.com
ARIAD Announces Initiation Of Ponatinib (AP24534) Pivotal Trial In Drug-Resistant Or Intolerant Chronic Myeloid Leukemia
September 2010, Medical News Today
Phase 2 trial of ponatinib for the treatment of chronic myeloid leukemia (CML) and Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL)
September 2010, MPR
