Nora C. Heisterkamp - CML -  Chronic Myeloid Leukemia 

Pediatrics, Pathology (Division of Hem-Onc)
Keck School of Medicine
The Saban Research Institute
Childrens Hospital Los Angeles
''Accomplishments in the area of cancer research and our main previous focus include the unraveling of major aspects of the molecular basis of chronic myeloid leukemia (CML) and Ph-chromosome positive acute lymphoblastic leukemia (ALL): during the period of 1981-1984, we identified two genes, BCR and ABL, which become fused as a result of a chromosomal translocation in CML and Ph-positive ALL. Research projects in our laboratory continue to concentrate on the signalling processes perturbed by BCR/ABL which lead to chronic myeloid and acute lymphoblastic leukemia, using in vitro and in vivo techniques. We also are studying gene products related to Bcr and Abl (Abr and Fer) to gain further understanding of the cellular function of those families of proteins''
Extract of http://pibbs.usc.edu/faculty/profile/?fid=225
More about  Nora Heisterkamp, PhD
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