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      • Dr. Elisabeth Buchdunger
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    • Experts involved in developing dasatinib >
      • Dr. Jagabandhu Das
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    • Other CML experts in America >
      • Other CML experts in Canada >
        • Dr. Sarit Assouline
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      • Other CML experts in US >
        • Carolyn Blasdel, RN , FNP-BC, OCN
        • PATRICIA JAKEL, RN, MN, AOCN
        • Rey Garcia, RN, BSN
        • Dr. Ravi Bhatia
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      • Other CML experts in South America >
        • Dra Beatriz Moiraghi
        • Dr Carolina Pavlovsky
    • Other CML Experts in Europe >
      • Dr. Jane Apperley
      • Dr. Michele Baccarani
      • Pr. Agnès Buzyn
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      • Dr. Eliane Gluckman
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      • Pr Gregor Verhoef
    • Other CML experts in Asia >
      • Dr. Charles Chuah
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      • Dr. Kim Dong-Wook
    • Other CML experts in Africa >
      • Dr. Anthony Oyekunle
    • Other CML experts in Australia >
      • Dr. Susan Branford
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      • Dr. Anthony P Schwarer
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  • Medication
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    • List of side effets >
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    • Cure possible for CML? >
      • Hematopoietic stem cell transplantation using single UM171-expanded cord blood
      • Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells
      • Inhibition of the protein Ezh2 can cure CML?
      • Combination of ruxolitinib with tyrosine kinase inhibitor
      • Combination of pioglitazone with tyrosine kinase inhibitor
      • Combination of miristen with tyrosine kinase inhibitor
      • Combination of Inecalcitol with tyrosine kinase inhibitor
      • Combination of dasatinib plus Nivolumab
      • Combination of Pembrolizumab with tyrosine kinase inhibitor
      • Combination of interferon with tyrosine kinase inhibitor
      • Combination of Venetoclax with tyrosine kinase inhibitor
      • PROTAC-mediated Targeted Protein Degradation
      • Inhibition of STAT5 in conjunction with standard TKI therapy
      • CML vaccine
      • Can immunotherapy cure leukemia?
      • Chimeric Antigen Receptor T-Cell Therapy
      • Can genetic sequencing help to cure leukemia?
      • Natural Medicine >
        • Possible cure for CML in Fish Oil
        • Betel leaf may help fight CML
        • Feverfew extract (parthenolide)
        • Can dandelions kill cancer?
        • Can curcumin cure leukemia?
      • Can the new drug CX-5461 cure leukemia?
      • CRISPR-Cas9 gene-editing technique
      • Presence of bcr abl fusion transcripts in healthy individua
      • Math could help cure leukemia
    • Treatment free remission (TFR ) >
      • The French trial called STIM (Stop Imatinib)
      • De-escalation of treatment
      • Tyrosine Kinase Inhibitor Withdrawal Syndrome in CML Patients
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  • Congresses, conferences, meetings ASH, ASCO, EHA ...
    • ASCO - American Society of Clinical Oncology >
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Chronic Myeloid Leukemia

Combination of interferon with tyrosine kinase inhibitor

Important notice: You must inform your CML doctor or a qualified doctor before using this drug. The material presented here is for information purposes only;  it is not a substitute for your physician’s guidance and care. ​            
VIDEOS


Dr. Hochhaus on TFS With Nilotinib in Patients With CML
June 3, 2016, OncLiveTV

Prof Andreas Hochhaus: Welt-CML-Tag und TIGER-Studie
October 4, 2012, Jan Geissler
​​
CLINICAL TRIALS

Phase II study of nilotinib plus pegylated interferon alfa-2b as first-line therapy in chronic phase chronic myeloid leukaemia aiming to maximize complete molecular response and major molecular response
April 9, 2018, Australian New Zealand  Clinical Trials Registry

Tasigna and Interferon Alpha Evaluation Initiated by the German Chronic Myeloid Leukemia Study Group - the TIGER Study (TIGER)
August 22, 2017,  ClinicalTrials.gov

 
ARTICLES


Peg-Interferon Αlpha 2b can improve molecular recurrences in the  TREATMENT-FREE REMISSION; A pilot study with 18-month follow-up
June 2018, EHA 2018

Nilotinib in Combination with Pegylated Interferon Alfa-2b for CP-CML Leads to High Molecular Response Rates: Interim Results of the Pinnacle Study
2017, ASH2017
​
Nilotinib Versus Nilotinib Combined to Pegylated-Interferon Alfa 2a in First-Line Chronic Phase Chronic Myelogenous Leukemia Patients. Interim Analysis of a Phase III Trial
2017, ASH2017

Interferon alpha 2 maintenance therapy may enable high rates of treatment discontinuation in chronic myeloid leukemia
February 25, 2015, Leukemia

Tyrosine Kinase Inhibitors and Interferon
January 2 , 2014, NCBI   

Re-emergence of interferon-α in the treatment of chronic myeloid leukemia
December 14, 2012, Leukemia

Imatinib plus Peginterferon Alfa-2a in Chronic Myeloid Leukemia
December 23, 2010, The New England Journal of Medicine
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