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Chronic Myeloid Leukemia

Iclusig (Ponatinib) - Chronic Myeloid Leukemia - CML

 

SITES

Picture

Ponatinib (Ariad)


FORUMS

Ponatinib by LLS Group discussion
Iclusib by CML2 support group
Ponatinib by NewCMLDrug.Com
Ponatinib on  Facebook

BLOGS

Hans’s Blog

CLINICAL TRIALS

Ponatinib for CML Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL) (PACE)
Expanded Access Program of Ponatinib
 

ARTICLES


“Borne Out of Necessity and Data”:  Conquering Mutations in Leukemia
February 6, 2013, PLOS  Blog

New TKI Ponatinib Effective in Resistant  CML
February  2013, Clinical Oncology  News

Ponatinib Could Herald “Revolution”in CML  Treatment
December 20, 2012, OncLive

Ponatinib in Refractory Philadelphia  Chromosome–Positive  Leukemias
November 29, 2012, The  New England  Journal of Medicine

F.D.A. Gives Early Approval to Drug for Rare Leukemia
December 14, 2012,  The New York  Times

OHSU-developed ponatinib wins FDA  approval
December 14, 2012, Portland Business  Journal

FDA grants approval for potential  ‘blockbuster’ leukemia drug made by Cambridge-based Ariad
December 14, 2012, Boston.com
 
FDA Approves Ponatinib to Treat  Leukemia
December 14, 2012, Cancer  Network

ARIAD Announces Accelerated Approval by FDA of Iclusig (Ponatinib) for Patients with CML and Ph+ ALL Resistant or
Intolerant to Prior Tyrosine Kinase Inhibitor Therapy

December 14, 2012, Ariad
 
FDA Approves Ariad Pharma Leukemia  Drug
December 14, 2012, The Street

Study Brings Positive Results For the Most Resistant Types of  CML   VIDEO
December 12, 2012, Patient  Power

Ponatinib  offers new hope in drug-resistant leukemia
December 5, 2012 , News-Medical.net
 
Chronic Myeloid Leukemia Mutation Thwarted By Ponatinib
December 2, 2012,  Science  2.0

Data Published on ARIAD Candidate - Analyst  Blog
November 30, 2012, Nasdaq

In CML, Next-Generation TKIs Aim to Boost  Outcomes

November 30, 2012, Onc  LIve

Ponatinib - New Pill Could Do Wonders for Cancer  Patients
November 30, 2012, FM  NEWS 101 KXL

Ponatinib - Cancer pill targets previously impenetrable disease-causing gene mutation in leukemia patients
November 29, 2012, OHSU

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia
November 29, 2012,
News Medical

Ponatinib for Chronic Myeloid Leukemia
November 29, 2012, The New England  Journal of Medicine

Ponatinib acts against the most resistant types of chronic myeloid leukemia
November 28, 2012,
Science Codex

Ponatinib Acts Against the Most Resistant Types of Chronic Myeloid Leukemia
November 28, 2012,
Science Daily

Ariad CEO discusses company’s battle against cancer
November 8, 2012, Boston Herald

PropThink: Management says Ariad is Well-Prepared for Ponatinib Launch
November 7, 2012,
Reuters

FDA Agrees to Speed Review of Ariad Drug
October 25, 2012,
DailyFinance

Ariad: FDA doing priority review of leukemia drug
October 23, 2012,
CBSNews.com

Ariad Pharma downgraded on gains over last year
October 23, 2012,
CBS News

PropThink: ARIAD Building an Oncology Business Around Discovery, Development, and Commercialization
October 4, 2012,
Reuters

Ariad Pharmaceuticals: Ponatinib Approval Anticipated In Second-Line CML
October 1, 2012,
Seeking Alpha

ARIAD Announces Submission of Marketing Authorization Application for Ponatinib to the European Medicines Agency
August.
30, 2012, ARIAD Pharmaceuticals, Inc.

Ariad seeks approval for leukemia drug in Europe
August 30, 2012, MHT

Ariad Pharmaceuticals Gearing Up For Ponatinib's Approval

August 29, 2012,
Seeking  Alpha

ARIAD Pharma initiates phase I/II trial of ponatinib in Japan
August 22, 2012, Pharmabiz.com

Ponatinib Produces High Response Rates in CML
August 13, 2012, New Mexico Cancer Center

Accelerated FDA Approval for CML Drug Ponatinib Sought
August 9, 2012, Cancer Network

Ponatinib Achieves Primary Endpoints in CML Subtypes
August 8, 2012, OncLive

Ariad Prepares for Early Launch of CML Drug Ponatinib
August 6, 2012, Oncology Stat

Ariad speeds targeted leukemia drug to FDA in race for key approval
July 31, 2012, FierceBiotech

Ariad Pharma ANNOUNCES Phase 3 Trial and 4 Stocks Hitting 52-Week Highs

July 28, 2012, Wall St . Cheqt  Sheet


Dr. Jorge Cortes Discusses the Ponatinib Ph+All and CML Evaluation (PACE) Trial             VIDEO
June 14, 2012, OncLive
             
Platelet dysfunction associated with ponatinib, a new  pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to  multiple tyrosine kinase inhibitor therapy

April 24, 2012, Haematologica

ARIAD: Xiaotian Zhu on Ponatinib                                                                  VIDEO
April 3, 2012, Executive video
Dr. Jorges Cortes: ASH2011 - Two New Winners for CML?                                VIDEO
December 23, 2011, 
Medscape News Today

Ariad Pharmaceuticals Still Might Have Upside
December 21, 2011, Investor Place

Waging War Against Chronic Myeloid  Leukemia 
Chronic Myeloid Leukema  responds well to experimental drug ponatinib
December 20, 2011, DailyRX

Ariad's ponatinib takes center stage with promising pivotal leukemia data
December 12, 2011, Fierce Biotech

Drug For Chronic Myeloid Leukemia To Be Out Soon
December 12, 2011, TopNews

Initial Findings from the PACE trial: A Pivotal Phase 2 Study of Ponatinib in Patients with CML and Ph+All
Resistant or Intolerant or Dasatinib or Nilotinib, or with the T315I  Mutation

December 2, 2011, Ariad

Ariad Pharma: Early Efficacy, Safety of Leukemia Drug 'Striking'
November  7, 2011, The Street

ARIAD Presents New Preclinical Data On Ponatinib In Solid Tumors, Demonstrating Inhibition Of All FGF Receptor Kinases

April 6, 2011,  Medical News Today

Phase I Trial Shows Ponatinib May Thwart Most Resistant CML
December 16, 2010,  MD Anderson Cancer Center -  Department of Leukemia

Updated Phase 1 study data of ponatinib in  patients with refractory CML, Ph+ ALL presented at ASH
December 6, 2010 , News medical

Novel CML Drug Active After Failures of Imatinib, Dasatinib, and Nilotinib

December 6, 2010, Oncology Stat

Phase I Trial Indicates Ponatinib May Thwart Most Resistant CML
December 2010, Drugs.com
 
ARIAD Announces Initiation Of Ponatinib (AP24534) Pivotal Trial In Drug-Resistant Or Intolerant Chronic Myeloid Leukemia
September 2010, Medical News Today

Phase 2 trial of ponatinib for the treatment of chronic myeloid leukemia (CML) and  Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL)
September 2010, MPR

 











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