Food and Drug Interactions - Chronic Myeloid Leukemia
Drug & food interactions
July 2011, The National CML Society
Effects of Selected Natural Health Products on Drug Metabolism:
Implications for Pharmacovigilance
2011, University of Ottawa
Gleevec Interactions
November 2010, Gist Support International
Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib
See the table on a pdf file
August 2010, Journal Blood
Gleevec-Food/Beverage Interactions
October 2008, Novartis
Drug/Food Interaction Chart
2004, CML Society of Canada
July 2011, The National CML Society
Effects of Selected Natural Health Products on Drug Metabolism:
Implications for Pharmacovigilance
2011, University of Ottawa
Gleevec Interactions
November 2010, Gist Support International
Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib
See the table on a pdf file
August 2010, Journal Blood
Gleevec-Food/Beverage Interactions
October 2008, Novartis
Drug/Food Interaction Chart
2004, CML Society of Canada
Gleevec (Imatinib) Drug Interactions by Drugs.com
Tasigna (Nilotinib) Drug Interactions
Sprycel (Dasatinib) Drug Interactions
Tasigna (Nilotinib) Drug Interactions
Sprycel (Dasatinib) Drug Interactions
‘’Several fruits can also cause problems and patients should not drink grapefruit juice or eat grapefruits. Other fruits available in Australia which should be avoided include star fruit, mulberries and pomegranates. For more detailed information please talk to your doctor or visit http://en.wikipedia.org/wiki/CYP3A4 (this site lists drugs that interfere with the body’s ability to metabolise the drugs).
WHY GRAPEFRUIT INTERFERES WITH GLIVEC
Chronic myeloid leukaemia patients being treated with a tyrosine kinase inhibitor (TKI), such as Glivec®, are warned not to eat grapefruits or drink grapefruit juice. Grapefruit is one of several fruits and herbs which can stop TKIs from working. Grapefruit juice induces the lining of the stomach to produce cytochrome, which in turn metabolises the drug before it can reach the blood system.’’
February 2009, Extract of http://www.leukaemia.org.au/fileadmin/dl-docs/booklets/Carer_Feb09.pdf
Chronic myeloid leukaemia patients being treated with a tyrosine kinase inhibitor (TKI), such as Glivec®, are warned not to eat grapefruits or drink grapefruit juice. Grapefruit is one of several fruits and herbs which can stop TKIs from working. Grapefruit juice induces the lining of the stomach to produce cytochrome, which in turn metabolises the drug before it can reach the blood system.’’
February 2009, Extract of http://www.leukaemia.org.au/fileadmin/dl-docs/booklets/Carer_Feb09.pdf
Vitamin C and Cancer
Vitamin C supplements may undercut the effectiveness of cancer drugs including Novartis' Gleevec, a U.S. study published on Wednesday showed.
When used on human cancer cells treated with a form of vitamin C in lab dishes, chemotherapy drugs killed 30 percent to 70 percent fewer tumor cells than usual, the scientists wrote in the journal Cancer Research.
October 2008, Natural Health News
Vitamin C may blunt effect of chemotherapy: study
October 2008, Asiaone Health
Straight Talk on Vitamin C During Chemotherapy Treatment
January 2010, Pharmacist
HOME :: Cancer Straight Talk on Vitamin C During Chemotherapy Treatment
November 2008, Ezines Aricles
VITAMIN C - Good or Bad combined with Chemotherapy?
October 2008, Squidoo
Can Vitamin C Really Treat Cancer?
January 2009, Articlesbase


