Combinaison of hydroxychloroquine with tyrosine kinase inhibitor - CML - Chronic myeloid leukemia
ALERT
All TKI have the capacity to prolong the QTc interval and strongly interact with drugs such as chloroquine and azithromycin, 2 drugs that are currently evaluated against COVID-19. Combining these medications with TKI in the absence of medical prescription and supervision may lead to fatal torsade de pointe.
All TKI have the capacity to prolong the QTc interval and strongly interact with drugs such as chloroquine and azithromycin, 2 drugs that are currently evaluated against COVID-19. Combining these medications with TKI in the absence of medical prescription and supervision may lead to fatal torsade de pointe.
The potential for QT prolongation associated with nilotinib and dasatinib, although rare, necessitates vigilant monitoring.
VIDEOS
Chloroquine/Hydroxychloroquine for COVID-19 (Corona virus) Treatment: Use, MOA, Side-effects
April 2, 2020, Medinaz
David Karp, MD, PhD: ACR Recommendations for Hydroxychloroquine and COVID-19
March 30, 2020, HCPLive
COVID-19 : Hydroxychloroquine+Mechanism
March 21, 2020, DipMED
Hydroxychloroquine In Diabetes Treatment by Dr. Sushil Jindal
August 22, 2018, Docplexus
Hydroxychloroquine for Rheumatoid Arthritis
December 24, 2010, AlbertaRheumatology
Chloroquine/Hydroxychloroquine for COVID-19 (Corona virus) Treatment: Use, MOA, Side-effects
April 2, 2020, Medinaz
David Karp, MD, PhD: ACR Recommendations for Hydroxychloroquine and COVID-19
March 30, 2020, HCPLive
COVID-19 : Hydroxychloroquine+Mechanism
March 21, 2020, DipMED
Hydroxychloroquine In Diabetes Treatment by Dr. Sushil Jindal
August 22, 2018, Docplexus
Hydroxychloroquine for Rheumatoid Arthritis
December 24, 2010, AlbertaRheumatology
For doctors
Hydroxychloroquine Treatment for Covid-19: Case Studies for Doctors UPDATE - Doc Talk w/ Dr. Ban E29 (part 2)
April 1, 2020, Weightless4Life
Hydroxychloroquine treatment for Covid-19: Case Studies for Doctors - Doc Talk w/ Dr. Ban - Ep. 26 (part 1)
March 25, 2020, Weightless4Life
Hydroxychloroquine Treatment for Covid-19: Case Studies for Doctors UPDATE - Doc Talk w/ Dr. Ban E29 (part 2)
April 1, 2020, Weightless4Life
Hydroxychloroquine treatment for Covid-19: Case Studies for Doctors - Doc Talk w/ Dr. Ban - Ep. 26 (part 1)
March 25, 2020, Weightless4Life
ARTICLES
Ventricular Arrhythmia Risk Due to Hydroxychloroquine-Azithromycin Treatment For COVID-19
Mar 29, 2020, American College of Cardiology
A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease
January 10, 2020, PubMed
Hydroxychloroquine sensitizes chronic myeloid leukemia cells to Vγ9Vδ2 T cell-mediated lysis independent of autophagy
March 24, 2017, PubMed
Hydroxychloroquine Sensitizes Chronic Myeloid Cell to γ9δ2T Cell Mediated Lysis Independent of Autophagy
2016, Blood Journal
A trial of hydroxychloroquine with imatinib for chronic myeloid leukaemia (CHOICES)
January 15, 2015, Cancer Research UK
Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?
January 10, 2014, Taylor & Francis Online
Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?
2011, University of Glasgow
Ventricular Arrhythmia Risk Due to Hydroxychloroquine-Azithromycin Treatment For COVID-19
Mar 29, 2020, American College of Cardiology
A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease
January 10, 2020, PubMed
Hydroxychloroquine sensitizes chronic myeloid leukemia cells to Vγ9Vδ2 T cell-mediated lysis independent of autophagy
March 24, 2017, PubMed
Hydroxychloroquine Sensitizes Chronic Myeloid Cell to γ9δ2T Cell Mediated Lysis Independent of Autophagy
2016, Blood Journal
A trial of hydroxychloroquine with imatinib for chronic myeloid leukaemia (CHOICES)
January 15, 2015, Cancer Research UK
Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?
January 10, 2014, Taylor & Francis Online
Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?
2011, University of Glasgow
See also Side effects of TKIs on the heart
See also CML patients and the coronavirus
See also Dr. Tessa L Holyoake
Return to Cure possible for CML?
See also CML patients and the coronavirus
See also Dr. Tessa L Holyoake
Return to Cure possible for CML?