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Chronic Myeloid Leukemia

ASH 2013 - New Orleans - CML - Chronic  Myeloid Leukemia

2013 ASH Annual Meeting and Exposition December 7-10, 2013
    

CML Program

Saturday, December 7,  2013
Chronic Myeloid Leukemia:  Refining/Redefining the State of the  Art
631. Chronic Myeloid Leukemia: Biology  and Pathophysiology, excluding Therapy: Poster I 
632. Chronic Myeloid Leukemia: Therapy:  Poster I

Sunday,  December 8, 2013
Use of Tyrosine Kinase Inhibitors in  Myeloid Malignancies
632. Chronic Myeloid Leukemia: Therapy:  Key Clinical Updates
631. Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy: Poster II 
632. Chronic Myeloid Leukemia: Therapy: Poster II 
  
Monday,  December 9, 2013
632. Chronic Myeloid Leukemia: Therapy:  Early Surrogate Markers of Outcome, Long-Term Treatment and Treatment  Discontinuation
602. Disordered Gene Expression in  Hematologic Malignancy, including Disordered Epigenetic Regulation: Molecular  Mechanisms of Myeloid Leukemia
631. Chronic Myeloid Leukemia: Biology  and Pathophysiology, excluding Therapy: Targeting Malignant Stem Cells and the  Microenvironment in Chronic Myeloid Leukemia 
632. Chronic Myeloid Leukemia: Therapy:  Emerging Aspects of Monitoring and Long-Term  Treatment
631. Chronic Myeloid Leukemia: Biology  and Pathophysiology, excluding Therapy: Poster III 
632. Chronic Myeloid Leukemia: Therapy:  Poster III

Tuesday,  December 10, 2013
 631. Chronic Myeloid Leukemia: Biology  and Pathophysiology, excluding Therapy: Biologic Factors Impacting on  Alternative Therapeutic Strategies in Chronic Myeloid  Leukemia

NOTES

Abstracts and notes on CML presentations by Prof Steve O’Brien
2013, SPIRIT2, NewCastle Universisty
​
Forums  and Patient associations'reports

CML Advocates Network presents their adherence survey at ASH 2013 - poster available for download

Patient Advocate Point of View at  American Society of  Hematology (ASH)

ASH Report #2: First-line trial updates,  STOP trials, early switching, comorbidities, side  effects

ASH 2013  by  Cmlsupport (UK)
NEWS


Jorge E. Cortes, MD, and Michael J. Mauro, MD, provide expert perspective on the clinical implications of key study findings in chronic myeloid leukemia.
January 13, 2013, Clinical care options Oncology

Off and On Again Story of Ponatinib in  CML – by Michael Deininger, reporting from ASH 2013 
December 20, 2013, Medscape

Preclinical data shows BGB324 as  potential  treatment option for Chronic Myeloid  Leukemia
December 17, 2013, News  medical

Genetic Puzzle  Piece for Blood Cancers Found
December  12,  2013, MedPage Today
 
Bristol-Myers  Presents Long-term Data on Sprycel - Analyst  Blog
December 10, 2013, NASDAQ
 
Phase III studies demonstrate  superiority of Novartis' Tasigna over Glivec in newly diagnosed Ph+ CML patients
December 10, 2013, Pharmabiz.com

Preliminary Results from Bio-Path  Holdings’ Phase I Clinical Trial Presented at the Annual Meeting of the American  Society of Hematology (ASH) in New  Orleans
December 9, 2013, Business  Wire
 
ARIAD Loses as  EMA Deliberates on Iclusig - Analyst  Blog
December 9, 2013, Zacks.com
 
Four-Year Data from Phase 3 DASISION Trial Comparing Sprycel® (dasatinib) to Imatinib in First-Line Treatment of  Adults with Ph+ CP-CML Presented at  ASH  2013
December 9, 2013, Business  Wire

Excitement Over CAR-Engineered T-cells  in Leukemia and Lymphoma
December 9, 2013, Medscape
​
SOME  INTERESTING ABSTRACTS FOR CML

Vitamin D3 Analog Inecalcitol Synergizes with Imatinib To Inhibit Selectively The Growth Of Chronic Myeloid  Leukemia (CML) Progenitors and Stem  Cells

Frequent Mutations in the Calreticulin Gene CALR in Myeloproliferative  Neoplasms

The Genomic Landscape of Myeloproliferative Neoplasms: Somatic  CALR Mutations in the Majority of JAK2-Wildtype Patients

Ponatinib As Initial Therapy For  Patients With Chronic Myeloid Leukemia In Chronic Phase  (CML-CP)

Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia
                                       Return to other ASH Annual Meetings 
​
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